Caterpillar Fungus

Caterpillar fungus is a group of entomopathogenic fungi that infect and eventually emerge from insect larvae, making it an important system for studying host adaptation, fungal development, and natural product production. Infection begins when fungal spores attach to the larval cuticle, germinate, penetrate the body, and grow as hyphae that consume host tissues before producing a spore-bearing fruiting body. Genetic analyses help identify closely related species, trace population diversity, and reveal genes controlling pathogenicity, development, and compounds such as cordycepin. These findings support conservation of wild populations, improved cultivation of medicinal species, and investigation of fungal-host interactions.

Caterpillar Fungus - Related Videos

Research

JoVE Journal - Biology

A Simple Protocol for Extracting Hemocytes from Wild Caterpillars

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Cited by 26 •

2012

Insect hemocytes carry out many important functions, both immune and non-immune, throughout all stages of insect development. Our present knowledge of hemocyte types and function comes from studies on insect genetic models. Here, we present a method for extracting, quantifying and visualizing hemocytes from wild caterpillars.

Double-Staining Method: A Technique to Visualize Plant-Fungus Interactions Using Ruthenium Red and Lactophenol Cotton Blue

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2025

This video demonstrates a double staining method using ruthenium red and lactophenol cotton blue to visualize pectins and chitins during plant-fungus interactions in a coffee rust plant. The procedure helps understand plant defense mechanisms during fungal infections.

Research

JoVE Journal - Immunology and Infection
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Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

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Cited by 23 •

2019

This protocol outlines the establishment of a mouse model for studying Malassezia-host interactions in the skin. It describes the cultivation of Malassezia in vitro, the infection of the murine skin with Malassezia, and the subsequent analysis of the inflammation and the fungal burden in the skin tissue.

Double-Staining Method to Detect Pectin in Plant-Fungus Interaction

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Cited by 8 •

2022

This protocol describes a microscopical method to detect pectin in coffee-fungus interaction.

Research

JoVE Journal - Biochemistry
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Single-Step Enrichment of a TAP-Tagged Histone Deacetylase of the Filamentous Fungus Aspergillus nidulans for Enzymatic Activity Assay

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Cited by 5 •

2019

Class 1 histone deacetylases (HDACs) like RpdA have gained importance as potential targets to treat fungal infections. Here we present a protocol for the specific enrichment of TAP-tagged RpdA combined with an HDAC activity assay that allows in vitro efficacy testing of histone deacetylase inhibitors.

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