Cluster Identification

Cluster identification is the mathematical process of finding meaningful groups, or clusters, within a set of observations based on shared characteristics. It works by measuring relationships among data points and assigning them to groups using principles such as distance, similarity, density, or hierarchical linkage, depending on the chosen method. In mathematics and applied data analysis, cluster identification can reveal structure in complex datasets without requiring predefined labels. It supports applications such as pattern recognition, statistical exploration, image analysis, and classification, while helping researchers summarize variation, detect unusual observations, and formulate questions for further investigation.

Cluster Identification - Related Videos

Research

JoVE Journal - Engineering

Spatial Separation of Molecular Conformers and Clusters

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Cited by 3 •

2014

We present a technique that allows the spatial separation of different conformers or clusters present in a molecular beam. An electrostatic deflector is used to separate species by their mass-to-dipole moment ratio, leading to the production of gas-phase ensembles of a single conformer or cluster stoichiometry.

Research

JoVE Journal - Genetics
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

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Cited by 3 •

2017

Here we present a detailed protocol of (A) the identification of a natural product with antibiotic activity, (B) the purification of the compound, (C) the first model of its biosynthesis, (D) genome sequencing/-mining and the (E) verification of the biosynthetic gene cluster.

Research

JoVE Journal - Biology

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis

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Cited by 1 •

2022

This protocol describes a high-throughput clustered regularly interspaced short palindromic repeats (CRISPR) gene editing workflow for microRNA cluster network analysis that allows the rapid generation of a panel of genetically modified cell lines carrying unique miRNA cluster member deletion combinations as large as 35 kb within a single experiment.

Education

JoVE Core - Statistics

Cluster Sampling Method

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2023

Appropriate sampling methods ensure that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest. To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...

Vesicular Tubular Clusters

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2023

After budding out from the ER membrane, some COPII vesicles lose their coat and fuse with one another to form larger vesicles and interconnected tubules called vesicular tubular clusters or VTCs. These clusters constitute a compartment at the ER-Golgi interface known as ERGIC (Endoplasmic Reticulum Golgi Intermediate Compartment). The ERGIC is a mobile membrane-bound cargo transport system that sorts proteins secreted from ER and delivers them to the Golgi. With the help of motor proteins such...

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