Central Aortic Cannulation

Central aortic cannulation is a surgical technique that places a perfusion cannula directly into the ascending aorta to establish arterial access during cardiopulmonary bypass. After the aorta is exposed, a purse-string suture secures the insertion site, and the cannula delivers oxygenated blood from the bypass circuit into the systemic circulation while the heart and lungs are temporarily supported. This approach is widely used in open cardiac surgery, including valve repair or replacement and procedures requiring cardiac arrest, because it can provide direct, high-flow perfusion. Proper placement and control of the cannula help reduce bleeding, vessel injury, air embolism, and inadequate organ perfusion.

Central Aortic Cannulation - Related Videos

Research

JoVE Journal - Medicine

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

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Cited by 4 •

2017

Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.

Intraduodenal Cannulation in a Rat Model for Immunopathology Studies

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2025

This video demonstrates intraduodenal cannulation in a rat model. After anesthetizing the rat, the duodenum is located and a small puncture is created. A J-shaped cannula with a beveled tip is carefully inserted and secured, and the incision is closed. The cannulated rat model enables intra-intestinal infusion for immunopathology studies.

Aortic Ring Assay

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Cited by 42 •

2009

Angiogenesis, the sprouting of blood vessels from pre-existing vasculature, is associated with both natural and pathological processes. Here we demonstrate an aortic ring assay that allows angiogenic potentiators and inhibitors to be directly added to aortic rings in culture. Sprouting and neovessel outgrowth can be determined by inspecting the aortic rings over a period of 6-12 days.

Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct

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Cited by 17 •

2011

A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.

Cannulation of the Carotid Artery in a Rat Model

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2025

In this video, we demonstrate a surgical procedure to cannulate the left carotid artery in a rat model.

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