Functional Magnetic Resonance
Functional Magnetic Resonance - Related Videos
09:15
fMRI: Functional Magnetic Resonance Imaging
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2023
Functional magnetic resonance imaging (fMRI) is a non-invasive neuroimaging technique used to investigate human brain function and cognition in both healthy individuals and populations with abnormal brain states. Functional MRI utilizes a magnetic resonance signal to detect changes in blood flow that are coupled to neuronal activation when a specific task is performed. This is possible because hemoglobin within the blood has different magnetic properties depending on whether or not it is bound...
03:28
Functional Magnetic Resonance Spectroscopy of the Rat Barrel Cortex During Whisker Stimulation
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2025
Source: Blanc, J., et al. Functional Magnetic Resonance Spectroscopy at 7 T in the Rat Barrel Cortex During Whisker Activation. J. Vis. Exp. (2019)This video demonstrates the method of analyzing metabolic changes in the rat barrel cortex using functional magnetic resonance spectroscopy during whisker stimulation. Baseline metabolite spectra are compared with stimulated spectra to detect lactate increase in the barrel cortex, confirming successful neuronal activation.
11:37
Cardiac Magnetic Resonance Imaging
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2023
Source: Frederick W. Damen and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana In this video, high field, small-bore magnetic resonance imaging (MRI) with physiological monitoring is demonstrated to acquire gated cine loops of the murine cardiovascular system. This procedure provides a basis for assessing left-ventricular function, visualizing vascular networks, and quantifying motion of organs due to respiration. Comparable small animal...
03:46
Blood Oxygen Level-Dependent Functional Magnetic Resonance Imaging of the Visual Cortex
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2025
Source: Galenchik-Chan, A., et al. Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation. J. Vis. Exp. (2023). The video demonstrates functional magnetic resonance imaging (fMRI) of the visual cortex to map activity based on blood oxygenation levels. Structural MRI images are acquired as anatomical references, followed by fMRI scans. Visual stimuli are displayed to activate retinotopic neurons in the visual cortex. The increased energy demand...
10:25
Simultaneous Transcranial Alternating Current Stimulation and Functional Magnetic Resonance Imaging
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Cited by 18 •
2017
Transcranial alternating current stimulation (tACS) is a promising tool for noninvasive investigation of brain oscillations, though its effects are not completely understood. This article describes a safe and reliable setup for applying tACS simultaneously with functional magnetic resonance imaging, which can increase understanding oscillatory brain function and effects of tACS.
FAQs
The method relies on a hemodynamic response, meaning a change in local blood flow associated with activity. When a brain region becomes active, nearby blood flow and the balance between oxygenated and deoxygenated hemoglobin change. fMRI detects this blood-oxygen-level-dependent contrast as an indirect marker of regional function rather than recording neural activity itself.
Blood-oxygen-level-dependent contrast arises from physiological differences between oxygenated and deoxygenated hemoglobin. Activity in a brain region changes local blood flow, which shifts that balance and changes the magnetic signal detected by the scanner. This mechanism allows functional magnetic resonance to identify areas whose physiological state changes during rest or a task.
Pairing functional measurements with anatomical structure helps investigators relate a change in activity to a specific region of the living brain. That connection supports interpretation of findings involving behavior and cognition, rather than treating activity as an isolated signal. It also makes the method useful when researchers need both functional information and structural localization.
A study can measure the brain during rest or while a participant performs a task. These conditions allow researchers to examine physiological activity in relation to behavior and cognition. Comparing functional patterns across such settings can help investigate how living human brain systems operate and how their activity relates to medical questions.
Functional magnetic resonance can help relate active brain regions to nearby anatomical structures before surgery. This functional information gives clinicians a way to consider brain activity alongside anatomy when planning procedures. Its value comes from mapping function in the living patient, particularly when understanding the location of activity is relevant to a surgical decision.
Researchers use fMRI to study how brain activity relates to neurological and psychiatric disease. Measurements acquired during rest or a task can be examined alongside behavior and cognition, helping characterize functional changes in living human systems. The approach therefore supports disease-focused investigations while also showing how altered function relates to anatomical brain organization.