Iris Root Insertion
Iris Root Insertion - Related Videos
06:56
A System for Culturing Iris Pigment Epithelial Cells to Study Lens Regeneration in Newt
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Cited by 7 •
2011
In newt, the lens regenerates always from the dorsal iris by transdifferentiation of the iris pigmented epithelial cells (IPEs). Here we describe a procedure to culture dorsal and ventral newt IPE cells and their implantation to the newt eye. The implanted cells are then studied by tissue sectioning and immunohistochemistry.
11:04
Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)
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Cited by 2 •
2011
Quantitative, high-throughput, real-time, and label-free biomolecular detection (DNA, protein, etc.) on SiO2 surfaces can be achieved using a simple interferometric technique which relies on LED illumination, minimal optical components, and a camera. The Interferometric Reflectance Imaging Sensor (IRIS) is inexpensive, simple to use, and amenable to microarray formats.
05:22
Iris Fixation via External Pentagram Suturing
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2022
The present protocol describes how a 10-0 polypropylene suture crosses the anterior surface of the iris, forming a pentagram to prevent both iris and pupil from moving toward the cornea. This can be combined with subsequent keratoplasty to cure bullous keratopathy with extensive anterior synechia of the iris.
09:48
Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
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Cited by 9 •
2017
This protocol presents the use of a dorsal root ganglion (DRG) injection with a viral vector and a concurrent dorsal root crush injury in an adult rat as a model to study sensory axon regeneration. This model is suitable for investigating the use of gene therapy to promote sensory axon regeneration.
04:38
Modeling Sensory Axon Regeneration in a Rat Using Dorsal Root Ganglion Injection and Dorsal Root Crush Injury
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2025
Source: Cheah, M., et al. Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration. J. Vis. Exp. (2017).This video demonstrates a step-by-step procedure for injecting a viral suspension into the dorsal root ganglia (DRGs) and inducing a controlled axonal injury via a dorsal root crush in an anesthetized rat. The protocol involves exposing the DRGs, delivering a growth-promoting viral vector to facilitate axonal regeneration, and severing axonal...
FAQs
Its position and configuration help determine how the peripheral iris occupies the angle and how closely it relates to the trabecular meshwork. These anatomic relationships can produce a more open, narrow, or closed angle configuration. Because angle geometry affects access to the drainage tissue, iris root anatomy has direct relevance to aqueous outflow assessment.
The trabecular meshwork provides the principal route for aqueous humor to leave the eye, so its relationship with the peripheral iris is clinically important. Iris configuration may limit or preserve the available angle space around this tissue. Evaluating that relationship helps clinicians recognize structural conditions associated with impaired drainage and possible glaucoma.
Variations in iris root position and configuration affect the amount of angle space between the peripheral iris and the trabecular meshwork. When this relationship produces a narrow or closed angle, aqueous outflow may become structurally compromised. Recognizing the pattern helps distinguish angle anatomy that may require closer evaluation for glaucoma-related drainage problems.
Iris root insertion provides an anatomic reference for understanding the peripheral iris in relation to the anterior chamber angle. Its position helps clinicians interpret whether the angle appears sufficiently open for the trabecular meshwork to participate in aqueous drainage. This context supports more meaningful assessment than considering the peripheral iris without its attachment pattern.
During gonioscopy, the clinician examines the anterior chamber angle and evaluates the position and configuration of the iris root. The assessment focuses on how the peripheral iris relates to the angle and trabecular meshwork, allowing narrow or closed configurations to be identified. These observations contribute to the structural evaluation of glaucoma risk and aqueous outflow.
A narrow or closed appearance indicates that the peripheral iris has an important structural relationship to the angle and may limit access to the trabecular meshwork. Because that tissue is the principal aqueous outflow pathway, the finding raises concern for impaired drainage. Clinicians use this information to characterize angle anatomy and support glaucoma evaluation.
The insertion pattern helps clinicians identify structural angle configurations associated with impaired aqueous drainage, including narrow or closed angles. These findings support glaucoma assessment by linking visible anatomy with the potential behavior of aqueous outflow. The information can also help guide management decisions when clinicians consider approaches intended to preserve or restore drainage.
Assessment of the iris root gives clinicians structural information before selecting or planning procedures intended to preserve or restore aqueous outflow. A narrow or closed angle pattern may indicate that the relationship between the peripheral iris and trabecular meshwork requires particular attention. Thus, gonioscopic anatomy contributes to procedure-related decision-making in glaucoma care.