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May 03, 2011
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Summary
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Quantitative, high-throughput, real-time, and label-free biomolecular detection (DNA, protein, etc.) on SiO2 surfaces can be achieved using a simple interferometric technique which relies on LED illumination, minimal optical components, and a camera. The Interferometric Reflectance Imaging Sensor (IRIS) is inexpensive, simple to use, and amenable to microarray formats.
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Cite this Article
Lopez, C. A., Daaboul, G. G., Ahn, S., Reddington, A. P., Monroe, M. R., Zhang, X., Irani, R. J., Yu, C., Genco, C. A., Cretich, M., Chiari, M., Goldberg, B. B., Connor, J. H., Ünlü, M. S. Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS). J. Vis. Exp. (51), e2694, doi:10.3791/2694 (2011).
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