L5-s1 Fusion

L5-S1 fusion is a spinal surgery that joins the fifth lumbar vertebra to the first sacral vertebra, stabilizing the lumbosacral junction when pain or structural instability persists. The procedure typically removes a damaged intervertebral disc, places bone graft and sometimes an interbody cage between the vertebrae, and uses screws and rods to maintain alignment while new bone forms across the segment. In medicine, this technique may treat selected cases of degenerative disc disease, spondylolisthesis, spinal instability, or recurrent symptoms after other treatments have failed. By limiting painful motion, fusion can improve stability and function, although it permanently reduces movement at the treated level and requires careful patient selection.

L5-s1 Fusion - Related Videos

Research

JoVE Journal - Medicine

Full Endoscopic Interlaminar Approach for Paracentral L5-S1 Disc Herniation

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2023

Here, we present a protocol to describe the full endoscopic interlaminar approach (FEILA) technique, including every cutoff step required to reach technical proficiency. FEILA is a surgery with a relatively steep learning adaptation. Despite this, any surgeon capable of microdiscectomy can perform FEILA with enough practice and suitable patient selection.

Research

JoVE Journal - Neuroscience
Free Sample

Transforaminal Full-Endoscopic Lumbar Foraminotomy Under Local Anesthesia for L5/S1 Adjacent Segment Foraminal Stenosis

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Cited by 1 •

2025

This protocol provides a step-by-step guide for performing transforaminal full-endoscopic foraminotomy under local anesthesia. This motion-preserving technique is presented as a minimally invasive surgical alternative to fusion extension for treating L5/S1 foraminal stenosis in patients with adjacent segment disease.

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation

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Cited by 3 •

2022

Presented here is a novel technique of C-arm free transtubular posterolateral decompression for lumbar foraminal stenosis and lateral disc herniation under O-arm navigation.

Education

JoVE Core - Chemistry

Nuclear Fusion

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2020

The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons. A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...

Analysis of SNARE-mediated Membrane Fusion Using an Enzymatic Cell Fusion Assay

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2012

We have developed a cell fusion assay that quantifies SNARE-mediated membrane fusion events by activated expression of β-galactosidase.

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