Maternal Side Placenta
Maternal Side Placenta - Related Videos
12:40
Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue
0 Views •
Cited by 91 •
2016
Herein we describe methods for the dissection of fetal and maternal tissues from human term placenta, followed by isolation and expansion of mesenchymal stem/stromal cells (MSC) from these tissues.
14:42
Isolation and Analysis of Hematopoietic Stem Cells from the Placenta
0 Views •
Cited by 11 •
2008
We have identified the placenta as a major hematopoietic organ during development. We found that hematopoietic stem cells (HSCs) are both generated and expanded in the placenta in unique microenvironmental niches. Here, we describe experimental techniques required for isolation and visualization of HSCs in the mouse placenta.
07:51
Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
0 Views •
Cited by 44 •
2015
Described herein is a protocol to isolate and analyze the infiltrating leukocytes of tissues at the maternal-fetal interface (uterus, decidua, and placenta) of mice. This protocol maintains the integrity of most cell surface markers and yields enough viable cells for downstream applications including flow cytometry analysis.
08:08
Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
0 Views •
Cited by 56 •
2013
The ex vivo dual recirculating human placental perfusion model can be used to investigate the transfer of xenobiotics and nanoparticles across the human placenta. In this video protocol we describe the equipment and techniques required for a successful execution of a placenta perfusion.
11:44
A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
0 Views •
Cited by 11 •
2017
Presented here is a protocol for sampling of human placental villous tissue followed by isolation of cytotrophoblasts for primary cell culture. Treatment of trophoblasts with TNFα recapitulates inflammation in the obese intrauterine environment and facilitates the discovery of molecular targets regulated by inflammation in placentas with maternal obesity.
FAQs
Maternal spiral arteries deliver blood into the intervillous spaces, where it surrounds the chorionic villi. This arrangement places maternal blood close to the villous structures involved in exchange while preserving separate maternal and fetal circulations. Examining the maternal surface helps relate visible placental anatomy to the vascular pathway that supports maternal-fetal exchange during pregnancy.
Maternal and fetal blood normally remain in separate circulations within the placenta. Exchange occurs across the interface associated with the chorionic villi rather than through direct mixing of the two blood supplies. This principle helps clinicians interpret placental structure correctly and distinguish the maternal surface and its blood-filled spaces from the fetal circulation.
The basal plate forms the maternal attachment region, while the surface is organized into lobules called cotyledons. Their arrangement reflects how the placenta is structured at the uterine interface. Recognizing these features supports a systematic examination and helps determine whether the maternal surface appears complete or contains an area requiring further pathological evaluation.
The maternal surface can provide visible evidence relevant to pathology, including infarction, retained tissue, or abnormal attachment. These findings are interpreted alongside the surface anatomy rather than in isolation. Their recognition can guide closer examination of the placenta and support assessment of conditions affecting placental structure and maternal-fetal health.
After delivery, examination should focus on the maternal surface, its basal plate, and the cotyledons. The examiner assesses whether the surface appears complete and looks for tissue that may have been retained, areas suggestive of infarction, or evidence of abnormal attachment. This inspection connects gross anatomy with subsequent placental assessment.
A complete maternal surface should account for the expected cotyledonary lobules and basal plate. An absent or disrupted area can raise concern that placental tissue remains within the uterine interface. Checking completeness after delivery therefore provides an important anatomical assessment and may indicate when the placenta requires closer clinical or pathological review.
Maternal-side examination is useful after delivery and during interpretation of placental pathology. It helps document the placental attachment surface, assess completeness, and identify findings such as infarction or abnormal attachment. The resulting anatomical information contributes to evaluation of placental structure and supports broader interpretation of maternal-fetal health.
The maternal surface links the uterine attachment region with the placental structures that support exchange. Its appearance and integrity can therefore provide context for understanding placental function and pathology. In medicine, examining this region helps connect gross findings, vascular organization, and potential abnormalities with the overall assessment of pregnancy and maternal-fetal health.