Pneumatic Impactor Device
Pneumatic Impactor Device - Related Videos
03:24
Generating a Mouse Model of Traumatic Brain Injury Using an Impactor Device
0 Views •
2025
This video demonstrates the procedure for inducing traumatic brain injury (TBI) in a mouse model. An anesthetized mouse with an exposed skull is taken to create an opening in the skull, and then a controlled cortical injury is induced using an impact device. The injury damages the brain tissue, causing impaired cognitive function and motor coordination.
07:49
Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation
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Cited by 10 •
2016
This protocol describes a rod-based approach, combining 3D-printing and soft lithography techniques for fabricating the soft gripper devices. This approach eliminates the need for an external air source by incorporating a chamber component and reduces the chance of occlusion during the sealing process, particularly for miniaturized pneumatic channels.
03:58
Generating a Traumatic Brain Injury Mouse Model Using an Impactor Probe
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2025
This video demonstrates the procedure for inducing an open-skull traumatic brain injury in a mouse by making a midline skull incision, drilling through the skull and removing the bone flap to expose the brain cortex, and applying high pressure to induce trauma. The wound is then sutured to prepare the mouse model for subsequent experiments.
07:28
A Contusive Model of Unilateral Cervical Spinal Cord Injury Using the Infinite Horizon Impactor
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Cited by 46 •
2012
A reliable and repeatable way to produce a cervical unilateral spinal cord injury using the Infinite Horizon impactor is described. The method takes advantage of a custom designed frame and clamp to stabilize the spine. The standardized procedure and biomechanical injury parameters result in sufficient and sustained injuries.
09:34
Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment
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Cited by 6 •
2016
Herein, we describe the fabrication and operation of a double-layer microfluidic system made of polydimethylsiloxane (PDMS). We demonstrate the potential of this device for trapping, directing the coordination pathway of a crystalline molecular material and controlling chemical reactions onto on-chip trapped structures.
FAQs
Impact severity is shaped by several adjustable variables rather than pressure alone. Investigators can alter pneumatic pressure, impact velocity, penetration depth, and contact duration to control tissue deformation. Recording these settings helps relate a particular mechanical challenge to subsequent pathology or functional impairment, making comparisons between experimental conditions more interpretable.
The compressed-air system converts pneumatic energy into a brief mechanical event by propelling a piston or impact tip toward the target. This arrangement gives the investigator control over when contact occurs and how the tissue is deformed. Such timing and force control distinguishes a standardized model from an injury produced by an uncontrolled impact.
Timing matters because the device is designed to reproduce not only a force but also the temporal features of an impact. Specifying when and how long the tip contacts the target helps distinguish effects associated with the mechanical event itself. This is especially relevant when investigators compare injury conditions or track recovery after exposure.
A typical experimental workflow begins by selecting the target tissue and setting pressure, velocity, depth, and contact duration. The device then delivers the controlled impact through the piston or tip. Investigators can subsequently evaluate pathology, functional impairment, and recovery, using the resulting measurements to study the injury model or a potential treatment.
In medicine, the main application is preclinical modeling of traumatic brain injury, where controlled tissue deformation supports investigation of injury-related pathology and functional impairment. The same general approach can also be applied to other mechanical injuries. Defined exposure conditions help researchers examine how biological responses relate to specific impact settings.
These devices are useful when researchers need a reproducible injury before examining recovery or testing a potential intervention. After an impact, investigators can follow pathological changes and functional impairment, then assess recovery or treatment-related effects. The instrument therefore links a defined mechanical exposure with biological and therapeutic outcomes in a preclinical medicine setting.