Reconstructive Approaches

Reconstructive approaches are medical strategies that restore or improve the form and function of body structures altered by injury, disease, congenital differences, or previous treatment. They work by repairing damaged tissue or replacing it with carefully selected grafts, flaps, implants, or engineered materials, while preserving blood supply, supporting healing, and coordinating multiple stages of care when needed. In medicine, these approaches can improve mobility, appearance, organ function, and quality of life after trauma, cancer treatment, burns, or developmental conditions. Advances in microsurgery, biomaterials, and tissue engineering continue to expand the options for personalized reconstruction and functional recovery.

Reconstructive Approaches - Related Videos

Research

JoVE Journal - Medicine

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

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Cited by 11 •

2018

Methods for designing a computer-aided design/computer-aided manufacturing (CAD/CAM) surgical guide are shown. Cutting planes are separated, united, and thickened to easily visualize the necessary bone transfer. These designs can be three-dimensional printed and checked for accuracy.

Research

JoVE Journal - Developmental Biology

Detection and Quantitation of Label-Retaining Cells in Mouse Incisors using a 3D Reconstruction Approach after Tissue Clearing

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Cited by 3 •

2022

The mouse incisor contains valuable label-retaining cells in its stem cell niche. We have a novel way to unbiasedly detect and quantify the label-retaining cells; our study used EdU labeling and a 3D reconstruction approach after PEGASOS tissue clearing of the mandible.

Reconstruction of 3-Dimensional Histology Volume and its Application to Study Mouse Mammary Glands

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Cited by 9 •

2014

We present an image registration approach for 3-dimensional (3D) histology volume reconstruction, which facilitates the study of the changes of an organ at the level of macrostructures made up of cells . Using this approach, we studied the 3D changes between wild-type and Igfbp7-null mammary glands.

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction

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2025

This protocol presents a novel coronoid-temporalis pedicled flap (CTPF) technique for reconstructing small-to-medium orbital floor defects. CTPF avoids microvascular risks while maintaining biomechanical stability. Clinical cases demonstrate effective structural restoration, reduced complications, and preserved facial symmetry, offering a viable alternative to traditional grafts or alloplastic materials.

Research

JoVE Journal - Medicine
Free Sample

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

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Cited by 11 •

2020

Here, we propose a practical, feasible and reproducible evaluation guideline for computer-assisted reconstruction of the mandible in order to create uniformity between studies regarding postoperative accuracy evaluation. This protocol continues and specifies an earlier publication of this evaluation guideline.

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