Visualsonics Vevo 2100
Visualsonics Vevo 2100 - Related Videos
09:00
Murine Echocardiography and Ultrasound Imaging
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Cited by 61 •
2010
This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.
11:10
Generation and Phenotypic Characterization of a CRISPR/Cas9-Engineered Cracd-Deficient Mouse Model for Post-Myocardial Infarction Remodeling Studies
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2026
This protocol describes the generation and phenotypic characterization of a C57BL/6N-Cracdem1(c.538-83 to c.3352+255 del) mouse model using CRISPR/Cas9 technology to study the role of CRACD in cardiac remodeling following myocardial infarction.
11:50
High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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Cited by 9 •
2010
High frequency Doppler ultrasound is a novel technology for assessing regional myocardial function. This work presents first evidence demonstrating applicability of this versatile imaging platform for the repeated measure of myocardial strain, dp/dt, and mitral regurgitation in the ischemia-reperfused (IR) murine heart.
08:55
In vitro Transcription and Capping of Gaussia Luciferase mRNA Followed by HeLa Cell Transfection
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Cited by 13 •
2012
This method describes high yield in vitro synthesis of both capped and uncapped mRNA from a linearized plasmid containing the Gaussia luciferase (GLuc) gene. The RNA is purified and a fraction of the uncapped RNA is enzymatically capped using the Vaccinia virus capping enzyme. In the final step, the mRNA is transfected into HeLa cells and cell culture supernatants are assayed for luciferase activity.
07:34
Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
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2025
This study presents a protocol for establishing a reproducible, minimally invasive rat model of superior sagittal sinus thrombosis induced by ferric chloride, utilizing a silk-suture method in combination with laser speckle contrast imaging and high-resolution ultrasound for evaluation.
FAQs
The system sends ultrasound pulses through tissue and converts returning echoes into images. Researchers can interpret these images to examine anatomical structure, motion, and blood flow, linking morphology with physiological activity. Real-time acquisition adds temporal context, helping investigators observe changing biological processes rather than relying only on a static anatomical snapshot.
High-frequency ultrasound supports the system’s ability to produce detailed images of anatomical structures. This characteristic is particularly relevant to small-animal medical research, where investigators need to examine structures and physiological activity closely. The resulting detail helps studies assess anatomy alongside functional changes during cardiovascular, tumor, developmental, or disease-model investigations.
Because the imaging approach does not use ionizing radiation, researchers can perform noninvasive assessments without exposing subjects to that type of radiation. This supports repeated observations in longitudinal studies, allowing anatomical and physiological changes to be followed over time and compared with treatment responses or disease progression in the same subject.
A session can provide information about anatomical structures, movement, physiological activity, and blood flow. These measurements allow investigators to examine both structural and functional outcomes within a study. In medicine-focused research, that combination is useful for characterizing cardiovascular changes, evaluating tumors, studying development, and monitoring disease models.
Longitudinal monitoring allows researchers to repeat noninvasive measurements in the same subject instead of relying only on separate observations at different time points. This approach helps reveal how anatomy and function change during disease or treatment. It can also strengthen evaluation of emerging therapies by connecting treatment exposure with observed structural and physiological outcomes.
The system supports several areas of medical research, including cardiovascular imaging, tumor studies, developmental biology, and disease-model monitoring. Investigators can use it to assess anatomical changes, physiological activity, blood flow, or responses to treatment. Its ability to provide repeated, real-time observations makes it relevant when both progression and functional outcome matter.