Craniotomy Procedure
Craniotomy Procedure - Related Videos
09:25
A Craniotomy Surgery Procedure for Chronic Brain Imaging
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Cited by 182 •
2008
This video and protocol demonstrate how to implant a glass-covered cranial window in rodents. These preparations can be used for chronic in vivo two-photon imaging of the neocortex over time scales of months. It may also be used for other types of imaging, including optical intrinsic signal imaging.
10:05
A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
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Cited by 18 •
2017
This protocol presents a method for creating a large unilateral craniotomy over the temporal and parietal regions of the mouse cerebral cortex. This is especially useful for real time imaging over an expansive area of a cortical hemisphere.
12:16
Craniotomy Procedure for Visualizing Neuronal Activities in Hippocampus of Behaving Mice
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Cited by 3 •
2021
This article demonstrates the preparation of a custom-made imaging window supplemented with infusion cannula and its implantation onto the CA1 region of the hippocampus in mice.
08:30
A Method to Make a Craniotomy on the Ventral Skull of Neonate Rodents
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Cited by 6 •
2014
A surgical method is described to expose the ventral skull in neonate rats. Using this approach it is possible to open a craniotomy to perform acute electrophysiology and two-photon microscopy experiments in the brainstem of anesthetized pups.
11:58
Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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Cited by 2 •
2015
Minimally invasive thumb-sized pterional craniotomy for aneurysm clipping has afforded our patients with a shorter hospital stay at a lower cost compared to the national average.
FAQs
Securing the bone flap restores the skull’s continuity after the brain-directed work is complete. Because the removed section is preserved rather than discarded, the surgeon can close the operative site using the patient’s own bone. This supports a temporary access strategy while allowing the intervention to end with reconstruction of the opened area.
Opening the dura mater provides the next layer of access after the skull has been opened. The surgeon can then use microsurgical or image-guided techniques to approach the selected brain region. This layered sequence focuses the intervention on a target while helping limit unnecessary injury to healthy tissue.
These techniques help the surgeon reach a targeted region rather than approaching brain tissue without a defined objective. Microsurgical work supports controlled manipulation, while image-guided techniques help direct access to the intended location. Together, they support precise diagnosis or treatment and the goal of limiting injury to healthy tissue.
Access through a craniotomy can serve either a diagnostic or therapeutic objective, depending on the clinical need. The same operative route may support biopsy when tissue examination is needed or permit an intervention intended to treat a known problem. This flexibility makes the procedure relevant across both evaluation and active management.
During tumor resection, the targeted access allows the surgeon to work toward abnormal tissue, while vascular applications address vascular abnormalities. In both settings, the operative goal depends on reaching a specific region through the skull and dura. Microsurgical or image-guided methods can help maintain focus on that intended target.
Two distinct clinical aims are evacuation of bleeding and relief of pressure. The procedure provides a route to the relevant intracranial site so that the surgeon can address either bleeding or excessive pressure, rather than using the access solely for tumor or vascular treatment. These applications show its role in therapeutic intervention.
Beyond clinical treatment, craniotomy can provide access for research recording and direct study of brain structure and function. This connection allows the procedure to link observations made during neurosurgical care with investigations of how specific brain regions are organized or operate. Its value therefore extends from intervention to neuroscience research.