Biocompatible Devices
Biocompatible Devices - Related Videos
11:49
Autologous Endothelial Progenitor Cell-Seeding Technology and Biocompatibility Testing For Cardiovascular Devices in Large Animal Model
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Cited by 12 •
2011
A method for seeding titanium blood-contacting biomaterials with autologous cells and testing biocompatibility is described. This method uses endothelial progenitor cells and titanium tubes, seeded within minutes of surgical implantation into porcine venae cavae. This technique is adaptable to many other implantable biomedical devices.
03:47
Implantation of a Flexible Biocompatible Probe in a Glioblastoma Mouse Model
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2025
Source: Lefevre, M. C., et al., Flexible Organic Electronic Devices for Pulsed Electric Field Therapy of Glioblastoma. J. Vis. Exp. (2022)This video demonstrates the implantation of a flexible, biocompatible probe in a glioblastoma mouse model to deliver targeted pulsed electric field therapy for neurotherapeutic applications.
08:29
Thermal Measurement Techniques in Analytical Microfluidic Devices
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Cited by 6 •
2015
Here, we present three protocols for thermal measurements in microfluidic devices.
11:06
Fabrication of Fully Solution Processed Inorganic Nanocrystal Photovoltaic Devices
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Cited by 4 •
2016
This protocol describes the synthesis and solution deposition of inorganic nanocrystals layer by layer to produce thin film electronics on non-conductive surfaces. Solvent-stabilized inks can produce complete photovoltaic devices on glass substrates via spin and spray coating following post-deposition ligand exchange and sintering.
13:38
Synthesis of Biocompatible Liquid Crystal Elastomer Foams as Cell Scaffolds for 3D Spatial Cell Cultures
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Cited by 9 •
2017
This study presents a methodology to prepare 3D, biodegradable, foam-like cell scaffolds based on biocompatible side-chain liquid crystal elastomers (LCEs). Confocal microscopy experiments show that foam-like LCEs allow for cell attachment, proliferation, and the spontaneous alignment of C2C12s myoblasts.
FAQs
At the device interface, surface chemistry influences which proteins adsorb first. Those proteins can alter cellular attachment and shape immune responses. Consequently, changing the surface may affect whether surrounding cells associate with the device or whether inflammation develops. This makes surface design central to biological integration and device performance.
Mechanical compatibility determines how well a device’s physical behavior suits surrounding biological structures. The relevant properties work together with surface chemistry, degradation, and corrosion resistance to influence performance. In bioengineering, considering these factors collectively connects device design with cellular attachment, immune responses, and the risk of failure rather than treating mechanical behavior as the only criterion.
Degradation behavior and corrosion resistance address how a device changes during contact with its biological environment. These factors can influence material performance and surrounding responses, including inflammation or toxicity. Evaluating them is important when a device must remain functional while exposed to living tissues or fluids, because material changes at the interface can compromise safe operation.
For implants and prostheses, biocompatibility must be considered alongside the device’s intended mechanical role. Surface chemistry can influence protein adsorption and cellular attachment, while corrosion resistance and mechanical compatibility affect interaction with surrounding tissues. Attention to these linked properties supports integration and may reduce inflammation or failure, outcomes that directly influence device usefulness.
Biosensors and drug-delivery systems depend on appropriate interactions with biological fluids, cells, or tissues. Their material interfaces can affect protein adsorption and cellular responses, which may influence device performance. In bioengineering applications, examining surface chemistry, degradation behavior, and corrosion resistance helps connect material selection with safer diagnosis, treatment, or monitoring.
In tissue-engineering scaffolds, cellular attachment and degradation behavior are especially relevant because the material must interact with cells during the intended regenerative application. Surface chemistry can affect attachment, while material changes can influence the biological interface. Considering these factors helps bioengineers pursue better integration with biological systems and reduce inflammatory or toxic responses.