Multi-time Software

Multi-time software is a computational tool for organizing, analyzing, and comparing biological data collected across multiple time points or temporal scales. It works by aligning time-series measurements, linking observations to their acquisition times, and enabling changes in biological signals, structures, or populations to be examined longitudinally. In biology, this approach supports the analysis of time-lapse microscopy, developmental processes, cell behavior, and other experiments in which timing influences interpretation. By revealing patterns that may be missed in single-time-point measurements, multi-time analysis helps researchers quantify dynamic responses, compare experimental conditions, and generate more informative models of biological change.

Multi-time Software - Related Videos

Research

JoVE Journal - Biology

SpOT the Correct Tissue Every Time in Multi-tissue Blocks

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Cited by 5 •

2015

The purpose of the Specimen Orientation Tag (SpOT) is to function as an orientation tool to aid in individual tissue identification in multi-tissue paraffin blocks. These protocols demonstrate how it is constructed easily from common, low-cost histology materials and serves as a reliable visual marker in paraffin blocks and sections.

Research

JoVE Journal - Neuroscience
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Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

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Cited by 23 •

2014

Informational connectivity measures the correspondence between time courses of multi-voxel information across different brain regions. Multi-voxel pattern discriminability time series are extracted from regions and compared, revealing networks that are not identified in a typical functional connectivity approach.

Multi-Photon Time Lapse Imaging to Visualize Development in Real-time: Visualization of Migrating Neural Crest Cells in Zebrafish Embryos

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Cited by 7 •

2017

A combination of the advanced optical techniques of laser scanning microscopy with long wavelength multi-photon fluorescence excitation was implemented to capture high-resolution, three-dimensional, real-time imaging of neural crest migration in Tg(sox10:EGFP) and Tg(foxd3:GFP) zebrafish embryos.

VisualEyes: A Modular Software System for Oculomotor Experimentation

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Cited by 28 •

2011

Neural control and cognitive processes can be studied through eye movements. The VisualEyes software allows an operator to program stimuli on two computer screens independently using a simple, custom scripting language. The system can stimulate tandem eye movements (saccades and smooth pursuit) or opposing eye movements (vergence) or any combination.

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver

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Cited by 1 •

2025

The ValsalvaAnalyzer software includes functions to analyze continuous beat-to-beat electrocardiogram and blood pressure (BP) measurements recorded during the Valsalva maneuver (VM). The computed clinical biomarkers and estimated model outputs provide insight into sympathetic and parasympathetic regulation of heart rate and BP during the VM.

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