Vector-borne Diseases
Vector-borne Diseases - Related Videos
02:44
The Born-Haber Cycle
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2020
Lattice Energy An ionic compound is stable because of the electrostatic attraction between its positive and negative ions. The lattice energy of a compound is a measure of the strength of this attraction. The lattice energy (ΔHlattice) of an ionic compound is defined as the energy required to separate one mole of the solid into its component gaseous ions. Here, the convention is used where the ionic solid is separated into ions, meaning the lattice energies will be endothermic (positive...
08:33
Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector
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Cited by 12 •
2016
This manuscript describes how viral vector-mediated local gene delivery provides an attractive way to express transgenes in the central nervous system. The protocol outlines all crucial steps to perform a viral vector injection in the substantia nigra of the rat to develop a viral vector-based animal model for Parkinson's disease.
05:13
A Viral Vector Injection into the Rat Substantia Nigra for Neurodegenerative Disease Modeling
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2025
This video demonstrates the process of injecting a viral vector into the rat substantia nigra to model Parkinson's disease. It outlines the steps for preparing the rat, microinjecting the viral vector into the substantia nigra, and the recovery procedure.
09:00
Studying the Integration of Adult-born Neurons
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Cited by 11 •
2011
A way to study the integration of newborn dentate granule cells in adult animals is described. This technique uses an engineered retrovirus to label newborn neurons, followed by electrophysiological recordings to determine in vivo functional integration.
16:44
Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging
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Cited by 15 •
2009
We suggest a Born normalized approach for Optical Projection Tomography (BnOPT) that accounts for the absorption properties of imaged samples to obtain accurate and quantitative fluorescence tomographic reconstructions. We use the proposed algorithm to reconstruct the fluorescence molecular probe distribution within small animal organs.
FAQs
After a vector acquires a pathogen while feeding, the agent may multiply or undergo developmental changes before it becomes available for transmission. This interval links the pathogen’s biology to the vector’s life cycle and determines whether a later feeding event can expose another host. Examining these changes helps explain transmission patterns and supports disease surveillance.
Saliva and contaminated mouthparts provide the immediate route by which a pathogen moves from an infected vector to a new host. Feeding therefore connects vector behavior, pathogen location, and host exposure in one event. Studying this interaction helps biologists identify where transmission occurs and informs strategies aimed at reducing vector contact or population size.
Vector life cycles matter because transmission depends on more than the pathogen alone. Researchers consider when vectors acquire an agent, how the agent changes inside them, and when vectors later feed on other hosts. Linking these stages clarifies host interactions and can reveal points at which surveillance or control efforts may reduce transmission.
Environmental conditions influence risk by shaping vector populations, their life cycles, and opportunities to contact hosts. For this reason, biology-based risk prediction examines environmental context alongside pathogen development and host interactions. The resulting information can guide habitat management and help identify periods or locations where surveillance should be strengthened.
Surveillance brings together observations of vectors, pathogens, hosts, and relevant environmental conditions. Investigators can use knowledge of life cycles and pathogen development to interpret where transmission may occur and to anticipate changing risk. These findings support public-health decisions, including targeted monitoring, risk prediction, and selection of appropriate vector-control measures.
Control programs can combine vaccination with insecticide use, habitat management, and reduction of vector populations. These approaches act at different points in the transmission system: vaccination addresses host protection, while the remaining measures target vector contact, habitat, or abundance. Choosing among them depends on understanding the biology of the vector, pathogen, and host.