Holosystolic Murmur

A holosystolic murmur is a heart sound that begins with the first heart sound and persists without interruption through the second, signaling abnormal blood flow during ventricular contraction. It typically results from a sustained pressure gradient that drives turbulent flow, as in mitral or tricuspid regurgitation, or through a ventricular septal defect; its intensity often remains relatively uniform throughout systole. Clinical evaluation considers the murmur’s location, radiation, quality, and response to maneuvers that alter preload or afterload. Recognizing these features helps clinicians identify structural heart disease, guide echocardiographic assessment, estimate severity, and select appropriate monitoring or treatment.

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JoVE Science Education - Clinical Skills

Cardiac Exam III: Abnormal Heart Sounds

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2023

Source: Suneel Dhand, MD, Attending Physician, Internal Medicine, Beth Israel Deaconess Medical Center Having a fundamental understanding of normal heart sounds is the first step toward distinguishing the normal from the abnormal. Murmurs are sounds that represent turbulent and abnormal blood flow across a heart valve. They are caused either by stenosis (valve area too narrow) or regurgitation (backflow of blood across the valve) and are commonly heard as a "swishing" sound during auscultation.

Cardiac Exam II: Auscultation

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2023

Source: Suneel Dhand, MD, Attending Physician, Internal Medicine, Beth Israel Deaconess Medical Center Proficiency in the use of a stethoscope to listen to heart sounds and the ability to differentiate between normal and abnormal heart sounds are essential skills for any physician. Correct placement of the stethoscope on the chest corresponds to the sound of cardiac valves closing. The heart has two main sounds: S1 and S2. The first heart sound (S1) occurs as the mitral and tricuspid valves...

Proper Adjustment of Patient Attire during the Physical Exam

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2023

Source: Jaideep S. Talwalkar, MD, and Joseph Donroe, MD, Internal Medicine and Pediatrics, Yale School of Medicine, New Haven, CT In order to optimize the predictive value of the physical examination, the provider must perform maneuvers correctly. The proper use of drapes is an important component of correctly performing physical examination maneuvers. Skin lesions are missed when "inspection" occurs through clothing, crackles are erroneously reported when the lungs are examined through a...

The Comprehensive Infant Examination

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2023

Source: Heather Collette and Jaideep Talwalkar; Yale School of Medicine The newborn exam is important in establishing a baby's baseline health status as they enter the world. Newborn providers have the unique opportunity to evaluate a patient for the very first time. They are also tasked with identifying congenital anomalies that require early intervention to promote a long and healthy life for the child. Many newborn anomalies, such as heart defects, are noted on prenatal ultrasound. However,...

Using Point of Care Ultrasound to Augment Acquisition of Physical Exam Skills: Organs

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2023

Source: Joseph H. Donroe, Rachel Liu; Yale School of Medicine, USA Point of care ultrasound (POCUS) is used by clinicians for diagnosis, ongoing monitoring, and/or procedural guidance at the time of patient care. Many medical schools are now teaching POCUS as a part of their basic clinical skills training, in addition to history, physical exams, and clinical reasoning. Besides being an independent skill, POCUS is also an incredibly useful tool for augmenting the teaching and learning of the...

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