Grasping Test

The Grasping Test is a neurological examination that assesses an involuntary hand-closing response and helps identify abnormal reflex activity in the adult nervous system. During the test, the examiner gently strokes the patient’s palm or places a finger in it; an involuntary grasp, persistent finger flexion, or difficulty releasing the examiner’s hand may indicate loss of normal cortical inhibition over primitive reflex pathways. The response is expected in infants but is generally suppressed in healthy adults. Clinicians use the test alongside other neurological assessments to support evaluation of frontal-lobe dysfunction, brain injury, stroke, and neurodegenerative disease.

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Research

JoVE Journal - Behavior
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Estimation of Contact Regions Between Hands and Objects During Human Multi-Digit Grasping

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Cited by 9 •

2023

When we grasp an object, multiple regions of the fingers and hand typically make contact with the object's surface. Reconstructing such contact regions is challenging. Here, we present a method for approximately estimating the contact regions by combining marker-based motion capture with existing deep learning-based hand mesh reconstruction.

Research

JoVE Journal - Behavior

Frame-by-Frame Video Analysis of Idiosyncratic Reach-to-Grasp Movements in Humans

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Cited by 7 •

2018

This protocol describes how to use frame-by-frame video analysis to quantify idiosyncratic reach-to-grasp movements in humans. A comparative analysis of reaching in sighted versus unsighted healthy adults is used to demonstrate the technique, but the method can also be applied to the study of developmental and clinical populations.

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

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Cited by 10 •

2020

Here, we present a protocol to use a curvelet transform-based, open-source MATLAB software tool for quantifying fibrillar collagen organization in the extracellular matrix of both normal and diseased tissues. This tool can be applied to images with collagen fibers or other types of line-like structures.

Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies

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Cited by 2 •

2023

The protocol summarizes the best practices to minimize microbial bioburden in a cleanroom environment and includes strategies such as environmental monitoring, process monitoring, and product sterility testing. It is relevant for manufacturing and testing facilities that are required to meet current good tissue practice standards and current good manufacturing practice standards.

Subsurface Defect Localization by Structured Heating Using Laser Projected Photothermal Thermography

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Cited by 7 •

2017

This method aims at locating vertical subsurface defects. Here, we couple a laser with a spatial light modulator and trigger its video input to heat a sample surface deterministically with two anti-phased modulated lines while acquiring highly resolved thermal images. The defect position is retrieved from evaluating thermal wave interference minima.

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