Intracavernous Pressure Recording

Intracavernous pressure recording is a diagnostic technique that measures pressure within the penile corpora cavernosa to assess erectile hemodynamics and vascular function. During testing, an intracavernosal injection of a vasoactive agent promotes smooth-muscle relaxation and arterial inflow, while a needle connected to a pressure transducer records pressure changes during erection and detumescence. Comparing intracavernous pressure with systemic arterial pressure helps evaluate arterial insufficiency and the corporal veno-occlusive mechanism, in which expanding erectile tissue restricts venous outflow. In medicine, these measurements support the assessment of erectile dysfunction and related disorders, complementing clinical history and other vascular investigations.

Intracavernous Pressure Recording - Related Videos

Research

JoVE Journal - Medicine

Cavernous Nerve Stimulation and Recording of Intracavernous Pressure in a Rat

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Cited by 6 •

2018

This study describes a simplified surgical procedure and technique for performing cavernous nerve stimulation with the isolation of the nerve-electrode complex using silicone glue and intracavernous pressure measurement.

Performing Cavernous Nerve Stimulation in Rats to Measure Intracavernous Pressure

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2025

This video demonstrates the isolation and stimulation of the cavernous nerve in an anesthetized rat to study blood pressure changes in the cavernous body.

Research

JoVE Journal - Biology
Free Sample

Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method

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Cited by 175 •

2009

The CODA 8-Channel High Throughput Non-Invasive Blood Pressure system measures the blood pressure in up to 8 mice or rats simultaneously. This tail-cuff system uses Volume Pressure Recording (VPR) to measure the blood pressure by determining the tail blood volume.

Pressure-polishing Pipettes for Improved Patch-clamp Recording

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Cited by 13 •

2008

This is a guide to modifying the shape of glass micropipettes. Specifically, by using heat and air pressure the taper is widened without increasing the tip opening, leading to lower pipette resistance. This is critical to obtain low noise recordings of small cells but is useful in many applications.

Recording Changes in Renal Sympathetic Nerve Activity in Response to Arterial Pressure in Rats

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2025

This video demonstrates a technique of studying the activity of renal sympathetic nerves (RSNs) in response to changes in arterial pressure in rats. Upon attaching a pressure-sensing catheter to the femoral artery, the renal sympathetic nerves are exposed. The nerves are then lifted onto a recording electrode, and their electrical activity is recorded. Next, a vasoconstricting drug is injected to elevate blood pressure, and corresponding changes in RSN activity are monitored.

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