Dergi
/
/
Bioconjugation ve radiosynthesis<sup> 89</sup>, Zr-DFO-etiketli antikorlar
JoVE Journal
Kimya
Bu içeriği görüntülemek için JoVE aboneliği gereklidir.  Oturum açın veya ücretsiz deneme sürümünü başlatın.
JoVE Journal Kimya
The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies

Bioconjugation ve radiosynthesis<sup> 89</sup>, Zr-DFO-etiketli antikorlar

16,875 Views

09:29 min

February 12, 2015

DOI:

09:29 min
February 12, 2015

20 Views
,

Özet

Automatically generated

Due to its multi-day radioactive half-life and favorable decay properties, the positron-emitting radiometal 89Zr is extremely well-suited for use in antibody-based radiopharmaceuticals for PET imaging. In this protocol, the bioconjugation, radiosynthesis, and preclinical application of 89Zr-labeled antibodies will be described.

Read Article