Rose Bengal Aracılı Fotodinamik Terapi ile Candida glabrate'de Minyon Kolonilerin İndüksiyonu

1.4K görüntülenme

1 kez atıf aldı

09:06 dk.

29 Mart 2024

10.3791/66549-v

29 Mart 2024

1.4K görüntülenme

Cai-Ying Yang^*¹^,² , Jia-Horung Hung^*³ , Chi-Jung Wu⁴^,⁵ , Zhao-Xiang Wang¹^,² , Shih-Han Wang⁶ , Hao-Chun Liaw² , I-Huang Lin³ , Chun-Keung Yu¹^,⁶ , Tak-Wah Wong²^,⁷^,⁸

¹Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, ²Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, ³Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, ⁴National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, ⁵Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, ⁶Insititute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, ⁷Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, ⁸Center of Applied Nanomedicine, National Cheng Kung University

^* These authors contributed equally

Candida spp. ilaç direncinde minyon kolonilerin önemi tam olarak araştırılmamıştır. Antimikrobiyal fotodinamik tedavi (aPDT), ilaca dirençli mantar enfeksiyonlarına karşı umut verici bir strateji sunmaktadır. Bu çalışma, gül bengal aracılı aPDT'nin Candida glabrata'yı etkili bir şekilde deaktive ettiğini ve küçük kolonileri indükleyerek benzersiz bir prosedür sunduğunu göstermektedir.

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0:00

Introduction

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