Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal

This content is Open Access.

T-wave Ion Mobility-mass Spectrometry

T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis

Article DOI: 10.3791/1985
July 31st, 2010


Summary July 31st, 2010

Ion mobility-mass spectrometry is an emerging gas-phase technology that separates ions, based on their collision cross-section and mass. The method provides three-dimensional information on the overall topology and shape of protein complexes. Here, we outline a basic procedure for instrument setting and optimization, calibration of drift times, and data interpretation.

Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter