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JoVE Journal
Neuroscience

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Ultrasound-Guided Microinjection into the Mouse Forebrain In Utero at E9.5
 

Ultrasound-Guided Microinjection into the Mouse Forebrain In Utero at E9.5

Article DOI: 10.3791/2047
November 13th, 2010

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Summary November 13th, 2010

In utero survival surgery in mice permits the molecular manipulation of gene expression during development. Here we describe the use of high-frequency ultrasound imaging to guide the injection of retroviral vectors into the mouse brain at embryonic day (E) 9.5.

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