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JoVE Journal
Immunology and Infection

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Antigen Specific In Vivo Killing Assay using CFSE Labeled Target Cells
 
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Antigen Specific In Vivo Killing Assay using CFSE Labeled Target Cells

Article DOI: 10.3791/2250
November 9th, 2010

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Summary November 9th, 2010

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Many infections elicit a strong CTL response, but occasionally, the quantity of responding cells does not correlate to control of the pathogen1. One measure of CTL quality is their ability to kill specifically2. CFSE labeling of target cells can be used to investigate this CTL response quality in vivo3,4.

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