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A Mouse Model of the Cornea Pocket Assay for Angiogenesis Study
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A Mouse Model of the Cornea Pocket Assay for Angiogenesis Study

A Mouse Model of the Cornea Pocket Assay for Angiogenesis Study

DOI:
10.3791/3077-v

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06:13 min

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August 18, 2011

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, , , , , ,
1National Eye Institute

Chapters

  • 00:05Title
  • 01:25Producing the Angiogenic Factor Pellets
  • 02:58Performing the Mouse Cornea Pocket Assay
  • 04:56Analyzing the Factor-Induced Angiogenesis
  • 05:30Conclusion

Summary

Automatic Translation

Automatic Translation

The cornea is unique in that it lacks vascular tissues. However, robust blood vessel growth and survival can be induced in the cornea by potent angiogenic factors. Therefore, the cornea can provide with us a valuable tool for angiogenic studies. This protocol demonstrates how to perform the mouse model of cornea pocket assay and how to assess the angiogenesis induced by angiogenic factors using this model.

Tags

Mouse ModelCornea Pocket AssayAngiogenesis StudyAngiogenic FactorsAngiogenic EffectPelletCornea LayersBasic Fibroblast Growth Factor (bFGF)

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