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JoVE Journal
Neuroscience

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Progenitor-derived Oligodendrocyte Culture System from Human Fetal Brain
 

Progenitor-derived Oligodendrocyte Culture System from Human Fetal Brain

Article DOI: 10.3791/4274
December 20th, 2012

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Summary December 20th, 2012

Primary, human fetal brain-derived, multipotential progenitor cells proliferate in vitro while maintaining the capacity to differentiate into neurons and astrocytes. This work shows that neural progenitors can be induced to differentiate through stages of the oligodendrocytic lineage by conditioning with select growth factors.

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