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En ortotopisk musemodel af Anaplastisk thyreoideakarcinom
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
DOI:

07:01 min

April 17, 2013

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Chapters

  • 00:05Title
  • 01:14Cell Preparation
  • 02:43Surgery Preparation
  • 03:54Surgical Access to Thyroid and Cell Injection
  • 04:44Post-operative Care and Tissue Collection
  • 05:30Results: Histological Verification of Anaplastic Thyroid Carcinoma
  • 06:35Conclusion

Summary

Automatic Translation

Generering af et ortotopisk musemodel af anaplastisk thyreoideakarcinom beskrives her. Denne teknik anvender kirurgisk placering af humane anaplastiske thyreoideacancerceller i skjoldbruskkirtlen hos immunsvækkede mus, hvilket skaber en mere klinisk relevant indstilling for at studere sygdomsprogression samt skærmen innovative terapeutiske indgreb.

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