Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Immunology and Infection

A subscription to JoVE is required to view this content.
You will only be able to see the first 2 minutes.

JoVE Journal Immunology and Infection
Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
Isolation of Mouse Lung Dendritic Cells
Journal (Immunology and Infection)
Isolation of Mouse Lung Dendritic Cells
Visualizing Macrophage Extracellular Traps Using Confocal Microscopy
Journal (Immunology and Infection)
Visualizing Macrophage Extracellular Traps Using Confocal Microscopy
 

Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

Article DOI: 10.3791/52556
March 12th, 2015 •
*1, *1, 1, 1, 1, 1, 1, 1
1Department of Microbiology and Immunology, New York Medical College
* These authors contributed equally

Chapters

Summary
Automatic Translation
March 12th, 2015

Forward genetics is a powerful approach to identify genes in intracellular pathogens important for resistance to cell autonomous immunity. The current approach uses innate immune cells, specifically macrophages, to identify novel Toxoplasma gondii genes important for immune evasion.

Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter