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JoVE Journal
Immunology and Infection

This content is Open Access.

Normal and Malignant Muscle Cell Transplantation into Immune Compromised Adult Zebrafish
 

Normal and Malignant Muscle Cell Transplantation into Immune Compromised Adult Zebrafish

Article DOI: 10.3791/52597
December 26th, 2014

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Summary December 26th, 2014

Here, we present a protocol for cell transplantation of zebrafish skeletal muscle and embryonal rhabdomyosarcoma (ERMS) into adult immune compromised rag2E450fs homozygous mutant zebrafish. This protocol allows for the efficient analysis of regeneration and malignant transformation of muscle cells.

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