High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

Kim V. Berghaus; Seok H. Yun; Giuliano Scarcelli

doi:10.3791/53468

Journal

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Bioengineering

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High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis

14,888 Views

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13:31 min

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December 22, 2015

DOI:

10.3791/53468-v

DOI:

10.3791/53468-v

•

13:31 min

December 22, 2015

•

2 Views

Kim V. Berghaus¹, Seok H. Yun^2,3, Giuliano Scarcelli¹

¹Fischell Department of Bioengineering,University of Maryland, ²Wellman Center for Photomedicine,Harvard Medical School, Massachusetts General Hospital, ³The Harvard-MIT Division of Health Sciences and Technology,Massachusetts Institute of Technology

Summary

Here we present a protocol to build a rapid Brillouin spectrometer. Cascading virtually imaged phase array (VIPA) etalons achieve a measurement speed more than 1,000 times faster than traditional scanning Fabry-Perot spectrometers. This improvement provides the means for Brillouin analysis of tissue and biomaterials at low power levels in vivo.