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JoVE Journal
Bioengineering

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Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
 

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Article DOI: 10.3791/54564 10:36 min October 17th, 2016
October 17th, 2016

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Summary

The assembly and use of a multimodal microendoscope is described which can co-register superficial tissue image data with tissue physiological parameters including hemoglobin concentration, melanin concentration, and oxygen saturation. This technique can be useful for evaluating tissue structure and perfusion, and can be optimized for individual needs of the investigator.

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Multimodal Imaging Spectroscopy Fiber-bundle Microendoscopy Non-invasive In Vivo Tissue Analysis Cancer Biology Therapy Effects Tissue Microstructure Tissue Perfusion Probe Endoscopy Techniques Probe Placement Accuracy High-resolution Imaging Technique Quantitative Spectroscopy Method Visual Demonstration Construction Calibration Fluorescence Microscopy Modality
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