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Hele genomet sekvensering av Candida glabrata for gjenkjenning av markører av soppdrepende resistens
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Hele genomet sekvensering av Candida glabrata for gjenkjenning av markører av soppdrepende resistens

Article DOI: 10.3791/56714-v • 08:46 min • December 28th, 2017
December 28th, 2017 •
*1, *1,2,3, 1,2, 1, 1, 1, 1, 1, 1, 4, 4,5, 6, 7, 1,3, 1,2,3
1Centre for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, 2Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR, 3Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, 4Department of Microbiology and Infectious Diseases, Canberra Hospital and Health Services, Australian National University Medical School, 5Infection Management Services, Australian National University Medical School, 6Department of Microbiology and Infectious Diseases, St. Vincent's Hospital, 7Department of Infectious Diseases, Peter MacCallum Cancer Centre
* These authors contributed equally

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Denne studien implementert hele genomet sekvenser for analyse av mutasjoner i gener overdragelse soppdrepende resistens i Candida glabrata. C. glabrata isolerer motstandsdyktig mot echinocandins, azoles og 5-flucytosine, ble rekkefølge for å illustrere metodikken. Mottakelighet profiler isolert korrelert med tilstedeværelse eller fravær av spesifikke mutasjonen mønstre i gener.

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Medisin problemet 130 Candida glabrata hele genomet sekvensering soppdrepende resistens echinocandins azoles 5-flucytosine genomet-bredt analyse
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