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Journal / Immunology and Infection / Heterologöz β2-Microglobulin ile Yarasa Major…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Heterologöz β2-Microglobulin ile Yarasa Major Histocompatibility Complex Class I'in Stabilitesi ve Yapısı
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Heterologöz β2-Microglobulin ile Yarasa Major Histocompatibility Complex Class I'in Stabilitesi ve Yapısı

Article DOI: 10.3791/61462-v • 11:17 min • March 10th, 2021
March 10th, 2021 •
*1,2, *3,4, *2,5, 1,2, 1,2, 2, 2, 4, 1, 4, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3Faculty of Health Sciences, University of Macau, 4CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 5Savaid Medical School, University of Chinese Academy of Sciences
* These authors contributed equally

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Protokol, farklı türlerden potansiyel β 2 mikroglobulin (β 2m)ikameyoluyla stabil majör histocompatibility complex (MHC) sınıfı I elde etmek için deneysel yöntemleri açıklar. MHC I'in homolog ve heterolog β2m ile stabilize edilen yapısal karşılaştırması araştırılmıştır.

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İmmünoloji ve Enfeksiyon Sayı 169 Majör histocompabilite antijen kompleksi (MHC) sınıf I molekülleri β2-mikroglobulin (β2m) karmaşık yapı peptit TCR tetramer
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