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Rat Intestinal Crypts Isolation and Intestinal Organoids Generation

June 23rd, 2023
*1, *1,2, 3,4, 1,5,6
1Department of Genetics, Yale School of Medicine, 2Department of Pediatrics, Yale School of Medicine, 3Department of Pediatrics/Gastroenterology and Hepatology, Yale School of Medicine, 4Department of Cellular and Molecular Physiology, Yale School of Medicine, 5Yale Stem Cell Center, Yale School of Medicine, 6Yale Cancer Center, Yale School of Medicine
* These authors contributed equally

Summary
Automatic Translation

Nous présentons ici un protocole permettant de générer des organoïdes intestinaux de rat et de les utiliser dans plusieurs applications en aval. Les rats sont souvent un modèle préclinique privilégié, et le système organoïde intestinal robuste répond au besoin d’un système in vitro pour accompagner les études in vivo .

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