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Rat Intestinal Crypts Isolation and Intestinal Organoids Generation

June 23rd, 2023
*1, *1,2, 3,4, 1,5,6
1Department of Genetics, Yale School of Medicine, 2Department of Pediatrics, Yale School of Medicine, 3Department of Pediatrics/Gastroenterology and Hepatology, Yale School of Medicine, 4Department of Cellular and Molecular Physiology, Yale School of Medicine, 5Yale Stem Cell Center, Yale School of Medicine, 6Yale Cancer Center, Yale School of Medicine
* These authors contributed equally

Summary
Automatic Translation

Her presenterer vi en protokoll for å generere tarmorganoider fra rotter og bruke dem i flere nedstrøms applikasjoner. Rotter er ofte en foretrukket preklinisk modell, og det robuste tarmorganoidsystemet fyller behovet for et in vitro-system som følger med in vivo-studier.

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