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Journal / Medicine / Murine Hindlimb Gangrene 모델에서 발판 혈관 구조의 고해상도 입체…
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Murine Hindlimb Gangrene 모델에서 발판 혈관 구조의 고해상도 입체 이미징
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Murine Hindlimb Gangrene 모델에서 발판 혈관 구조의 고해상도 입체 이미징

Article DOI: 10.3791/63284-v • 08:16 min • March 16th, 2022
March 16th, 2022 •
1, 1,2, 3, 1, 1,2, 4, 1,2, 1,2, 1,2
1Dewitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, 2Vascular Biology Institute, University of Miami Miller School of Medicine, 3University of Miami, 4Analytical Imaging Core Facility, University of Miami

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본 프로토콜은 FVB 마우스에서 뒷다리 괴저(hindlimb gangrene)를 유도하기 위해 대퇴골 동맥 및 정맥 전기응고와 산화질소 합성효소 억제제의 투여를 결합한 말초 동맥 질환의 독특하고 임상적으로 관련된 모델을 기술한다. 심장 내 DiI 관류는 풋패드 혈관 구조의 고해상도, 입체 영상화에 사용됩니다.

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의학 문제 181 힌지 허혈 괴저 대퇴 동맥 결찰 L-NAME DiI 관류 말초 동맥 질환 신생혈관화 혈관 신생
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