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Journal / Biochemistry / Fingeravtryck av kardiolipin i leukocyter genom…
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Biochemistry

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JoVE Journal Biochemistry
Fingeravtryck av kardiolipin i leukocyter genom masspektrometri för en snabb diagnos av Barths syndrom
Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
Journal (Biochemistry)
Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
Fluorescence Anisotropy as a Tool to Study Protein-protein Interactions
Journal (Biochemistry)
Fluorescence Anisotropy as a Tool to Study Protein-protein Interactions
 
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Fingeravtryck av kardiolipin i leukocyter genom masspektrometri för en snabb diagnos av Barths syndrom

Article DOI: 10.3791/63552-v • 06:48 min • March 23rd, 2022
March 23rd, 2022 •
*1, *2, 2, 2
1Medical School, Swansea University, 2Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro
* These authors contributed equally

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Detta protokoll visar hur man erhåller ett masspektrometriskt "fingeravtryck" av leukocytkardiolipin för diagnos av Barths syndrom. Bedömningen av förhöjt förhållande mellan monolysokardiolipin och kardiolipin diskriminerar patienter med Barths syndrom från kontrollhjärtsviktspatienter med 100% känslighet och specificitet.

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Biokemi utgåva 181
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