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Journal / Bioengineering / Digitale genkretser basert på CRISPR-Cas-systemer …
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Bioengineering

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JoVE Journal Bioengineering
Digitale genkretser basert på CRISPR-Cas-systemer og anti-CRISPR-proteiner
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Digitale genkretser basert på CRISPR-Cas-systemer og anti-CRISPR-proteiner

Article DOI: 10.3791/64539-v • 10:46 min • October 18th, 2022
October 18th, 2022 •
*1, *1, 1
1School of Pharmaceutical Science and Technology, Tianjin University
* These authors contributed equally

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CRISPR-Cas-systemer og anti-CRISPR-proteiner ble integrert i skjemaet til boolske porter i Saccharomyces cerevisiae. De nye små logiske kretsene viste god ytelse og utdypet forståelsen av både dCas9/dCas12a-baserte transkripsjonsfaktorer og egenskapene til anti-CRISPR-proteiner.

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Retraksjon utgave 188 CRISPR-Cas-systemet dSpCas9 denAsCas12a dLbCas12a type II-A anti-CRISPR-proteiner type V-A anti-CRISPR-proteiner gendigitale kretser Saccharomyces cerevisiae syntetisk biologi
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