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JoVE Journal Bioengineering
Circuitos digitales genéticos basados en sistemas CRISPR-Cas y proteínas anti-CRISPR
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Circuitos digitales genéticos basados en sistemas CRISPR-Cas y proteínas anti-CRISPR

Article DOI: 10.3791/64539-v • 10:46 min • October 18th, 2022
October 18th, 2022 •
*1, *1, 1
1School of Pharmaceutical Science and Technology, Tianjin University
* These authors contributed equally

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Los sistemas CRISPR-Cas y las proteínas anti-CRISPR se integraron en el esquema de puertas booleanas en Saccharomyces cerevisiae. Los nuevos circuitos lógicos pequeños mostraron un buen rendimiento y profundizaron la comprensión de los factores de transcripción basados en dCas9 / dCas12a y las propiedades de las proteínas anti-CRISPR.

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Retracción Número 188 sistema CRISPR-Cas dSpCas9 denAsCas12a dLbCas12a proteínas anti-CRISPR tipo II-A proteínas anti-CRISPR tipo V-A circuitos digitales de genes Saccharomyces cerevisiae biología sintética
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