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JoVE Journal Cancer Research
在 3D 类器官中模拟口腔-食管鳞状细胞癌
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在 3D 类器官中模拟口腔-食管鳞状细胞癌

Article DOI: 10.3791/64676-v • 10:43 min • December 23rd, 2022
December 23rd, 2022 •
*1, *1,2, 1, 1, 1, 1, 1, 1,3, 1,3, 4, 1,2, 1,5, 1,6, 1,7, 1,5, 1,2,5
1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University
* These authors contributed equally

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该协议描述了生成和表征鼠口腔 - 食管3D类器官的关键步骤，这些类器官代表通过化学致癌引起的正常，癌前和鳞状细胞癌病变。

Tags

癌症研究，第190期，
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