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A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity
JoVE Journal
Medicine
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JoVE Journal Medicine
A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity
DOI:

09:09 min

May 28, 2014

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Chapters

  • 00:05Title
  • 01:25Preparation of Surgical Instruments and Drugs
  • 01:55Orotracheal Intubation
  • 03:30Spinal Surgery
  • 07:23Results: C2 Injury and Respiratory Output
  • 08:44Conclusion

Summary

Automatic Translation

Respiratory failure is the leading cause of death following a cervical spinal cord injury. Having a reproducible, quantifiable, and reliable pre-clinical animal model of respiratory failure induced by a partial cervical injury will help to understand the subsequent respiratory and non-respiratory neuroplasticity and allow testing putative repair strategies.

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