Temple Grandin

Temple Grandin is an American animal behavior scientist, educator, and autism advocate known for applying behavioral science to improve livestock handling and for describing her experiences as an autistic thinker. Her approach examines how animals respond to sensory cues such as noise, light, shadows, and unfamiliar movement, then uses that knowledge to redesign facilities, handling routes, and restraint systems that reduce fear and encourage steady movement. These principles have informed more humane practices in cattle processing and other agricultural settings, while her writing and public work have increased understanding of autism, sensory processing, and the value of different cognitive perspectives in science and society.

Temple Grandin - Related Videos

Research

JoVE Journal - Behavior
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The Use of Traditional Fear Tests to Evaluate Different Emotional Circuits in Cattle

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Cited by 6 •

2020

Here, we present a protocol to conduct a variety of behavioral tests in cattle that have been designed to evaluate emotions. A battery of behavioral tests (open field test, startle test, bovine zero maze, exit velocity, pen score, and chute score) were conducted to evaluate different components of animal temperament.

Research

JoVE Journal - Medicine

Cecal Ligation Puncture Procedure

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Cited by 200 •

2011

The mouse model of cecal ligation and puncture as a valuable tool for the study of human sepsis.

Pull-down of Calmodulin-binding Proteins

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Cited by 19 •

2012

Calmodulin (CaM) pull-down assay is an effective way to investigate the interaction of CaM with various proteins. This method uses CaM-sepharose beads for efficient and specific analysis of CaM-binding proteins. This provides an important tool to explore CaM signaling in cellular function.

Post-embedding Immunogold Labeling of Synaptic Proteins in Hippocampal Slice Cultures

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Cited by 13 •

2013

The localization and distribution of proteins provide important information for understanding their cellular functions. The superior spatial resolution of electron microscopy (EM) can be used to determine the subcellular localization of a given antigen following immunohistochemistry. For tissues of the central nervous system (CNS), preserving structural integrity while maintaining antigenicity has been especially difficult in EM studies. Here, we adopt a procedure that has been used to preserve...

Development of a Refined Protocol for Trans-scleral Subretinal Transplantation of Human Retinal Pigment Epithelial Cells into Rat Eyes

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Cited by 17 •

2017

Subretinal injection has been widely applied in preclinical studies of stem cell replacement therapy for age-related macular degeneration. In this visualized article, we describe a less risky, reproducible and precisely modified subretinal injection technique via the trans-scleral approach to deliver cells into rat eyes.

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