Cellular Drinking
Cellular Drinking - Related Videos
07:31
Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
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Cited by 22 •
2019
Alcohol Use Disorder (AUD) is a major national health problem and the development of more effective treatments is required to offset the needs of this patient population. To this end, the following protocol utilizes two simple rodent drinking models to assess the preclinical efficacy of lead anti-alcohol compounds.
07:28
Web-based Clinician Guide to Record Compatible Video of Standardized Drinking Task Kinematics for Computer Vision Analysis
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2025
Kinematic metrics of the drinking task have been recommended for use in upper limb stroke rehabilitation, but conventional approaches to kinematic studies are considered impractical. The current protocol describes a web-based guide to capture videos of the drinking task, which are compatible with computer vision to extract recommended kinematic metrics.
05:00
Cellular Respiration - Concepts
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2019
Autotrophs and Heterotrophs Living organisms require a continuous input of energy to maintain cellular and organismal functions such as growth, repair, movement, defense, and reproduction. Cells can only use chemical energy to fuel their functions, therefore they need to harvest energy from chemical bonds of biomolecules, such as sugars and lipids. Autotrophic organisms, namely plants, algae, and photosynthetic and chemosynthetic bacteria, convert inorganic materials into such biomolecules by...
05:44
Cellular Respiration - Student Protocol
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2019
Quantifying Respiration using Microrespirometers ExpandNOTE: In this experiment, you will measure the rate of cellular respiration for germinating seeds by measuring the rate of exchange for oxygen. As oxygen is consumed to provide energy, germinating seeds release carbon dioxide. This carbon dioxide is absorbed by potassium carbonate and thus the overall gaseous pressure of the respirometer will be reduced. HYPOTHESES: The experimental hypothesis is that germinating seeds will show a greater...
11:19
Preparation and Testing of Impedance-based Fluidic Biochips with RTgill-W1 Cells for Rapid Evaluation of Drinking Water Samples for Toxicity
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Cited by 12 •
2016
This manuscript describes how to prepare fluidic biochips with Rainbow trout gill epithelial cells for use in a field portable electric cell-substrate impedance sensor. The protocol for running a rapid drinking water toxicity test with the sensor is also described.
FAQs
The membrane’s inward bending creates a temporary pocket that captures nearby extracellular fluid and dissolved solutes. As the pocket closes, the membrane pinches off, producing a small vesicle inside the cell. That vesicle provides a contained route for moving sampled material away from the cell surface, where the contents can be processed or delivered to organelles.
Unlike receptor-mediated endocytosis, pinocytosis is not primarily driven by highly selective recognition of particular extracellular molecules. It samples the local fluid and its dissolved contents, so the material entering a vesicle reflects the surrounding environment more broadly. This distinction makes the process useful for general uptake and for examining how cells interact with changing extracellular conditions.
Cellular drinking can also contribute to plasma-membrane turnover, because portions of the cell surface become incorporated into newly formed intracellular vesicles. The process therefore links uptake with the movement of membrane material. In addition to bringing fluid and solutes into the cell, it connects surface dynamics with intracellular transport pathways.
To follow the process conceptually, examine four linked events: extracellular fluid lies next to the plasma membrane, the membrane bends inward, the pocket encloses nearby fluid, and the neck pinches off. The resulting vesicle then moves its contents toward intracellular processing or delivery to organelles. This sequence organizes observations of cellular transport without assuming selective receptor binding.
The immediate product is an intracellular vesicle containing sampled fluid and dissolved substances. Its contents may undergo processing within the cell or be delivered to organelles, while the vesicle membrane participates in broader trafficking. Observing vesicle formation can therefore provide information about both cargo movement and the cell’s handling of its own membrane.
In biology, cellular drinking provides a framework for studying nutrient acquisition, regulation of fluid and solute balance, and communication with the extracellular environment. It also serves as a model for investigating vesicle trafficking and cellular transport. These applications connect a membrane-level event with larger questions about how cells obtain materials, regulate internal conditions, and exchange information.