Kidney Capsule
Kidney Capsule - Related Videos
03:00
Extracting Intact Kidney from Mouse: A Technique to Obtain Kidney Without Renal Capsule from Murine Models
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2023
In this video, we describe the procedure for kidney extraction from the retroperitoneal space of the mouse. The extracted kidney can further be microdissected to obtain an intact kidney without a renal capsule and the surrounding fat layer.
10:43
Transplantation of Pancreatic Islets Into the Kidney Capsule of Diabetic Mice
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Cited by 98 •
2007
Our protocol was developed to cleanly and easily deliver islets or cells under the kidney capsule of mice. Cells are concentrated into pellets in the final tubing used for transplanting the cells under the kidney capsule. The ease of this technique reduces stress to the cells and the mouse.
08:19
The Mouse Isolated Perfused Kidney Technique
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Cited by 24 •
2016
The mouse isolated perfused kidney (MIPK) is a technique for keeping a mouse kidney under ex vivo conditions perfused and functional for 1 hr. The buffers and surgical technique are described in detail.
01:45
Kidney Structure
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2019
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries. The renal cortex is the thick outer layer of the kidney. It...
05:24
Teratoma Generation in the Testis Capsule
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Cited by 25 •
2011
Human pluripotent stem cells (hPSCs) have the potential to treat a myriad of different diseases. The utility of these cells lies in the fact that they can differentiate into any cell type in the body. Here we describe the teratoma assay, which is used to demonstrate the pluripotence of hPSCs.
FAQs
The capsule forms a close-fitting boundary directly around the kidney, while surrounding fat and connective tissues lie outside it. This arrangement creates layered protection rather than a single uniform covering. Comparing these regions helps biologists distinguish the capsule’s collagen-rich structural role from the position and organization of tissues located around the organ.
Collagen-rich fibers help the capsule resist mechanical stress and retain the kidney’s overall shape. Their contribution is structural rather than simply superficial: the fibers form a tough connective-tissue layer that remains closely associated with the organ. This arrangement helps maintain a stable external framework around delicate renal structures, including nephrons and blood vessels.
Because it closely surrounds the kidney, the capsule provides a physical boundary that can limit the movement of inflammation or infection toward nearby structures. It does not eliminate disease processes, but its position and connective-tissue composition may restrict their local spread. This protective relationship makes the capsule relevant when considering how renal injury affects surrounding tissues.
The capsule lies outside the kidney’s internal tissues, yet its protective role is relevant to the nephrons and blood vessels contained within the organ. By helping preserve the kidney’s shape and resist external mechanical stress, it contributes indirectly to the physical protection of these structures. This relationship illustrates how tissue layers support internal organization.
An examination should consider the capsule’s position, close fit around the kidney, connective-tissue composition, and relationship to surrounding fat and connective tissues. It should also relate the outer layer to the organ’s internal organization, including nephrons and blood vessels. These observations support biological study of renal anatomy, tissue organization, and physical protection.
Changes in the capsule can provide clues about kidney injury, inflammation, scarring, or disease-related enlargement. These findings are interpreted as indicators of altered renal structure rather than as a complete explanation of the underlying condition. Examining the capsule alongside overall kidney anatomy helps connect visible tissue changes with broader patterns of renal damage or disease.