Magnetic Iron Particles

Magnetic iron particles are iron-containing micro- or nanoscale materials that respond to an applied magnetic field, making them useful tools for manipulating biological samples. Their iron or iron oxide cores develop magnetic behavior that allows external magnets to concentrate, separate, transport, or immobilize the particles without direct contact. In biology, researchers use these properties for isolating cells and biomolecules, supporting targeted delivery systems, enhancing imaging, and studying cellular processes. Particle size, surface coating, magnetic response, and biological compatibility influence performance, while controlled functionalization helps particles interact with specific cells, proteins, or tissues.

Magnetic Iron Particles - Related Videos

Research

JoVE Journal - Bioengineering

Fabrication of a Functionalized Magnetic Bacterial Nanocellulose with Iron Oxide Nanoparticles

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Cited by 42 •

2016

Here, we present a protocol to make a bacterial nanocellulose (BNC) magnetic for applications in damaged blood vessel reconstruction. The BNC was synthesized by G. xylinus strain. On the other hand, magnetization of the BNC was realized through in situ precipitation of Fe2+ and Fe3+ ferrous ions inside the BNC mesh.

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

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Cited by 5 •

2016

A scanner for imaging magnetic particles in planar samples was developed using the planar frequency mixing magnetic detection technique. The magnetic intermodulation product response from the nonlinear nonhysteretic magnetization of the particles is recorded upon a two-frequency excitation. It can be used to take 2D images of thin biological samples.

Growth and Differentiation of Magnetic Nano Particle-Loaded Neurons on Magnetic Platforms

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2025

This video demonstrates the uptake of fluorescent magnetic nanoparticles (MNPs) by the neuronal cells via endocytosis. Growing these MNP-loaded neurons on the magnetically patterned substrate enables the attachment of the cells. The addition of a growth factor containing medium aids in the growth of neuron extensions, while the magnetic field of the substrate directs the orientation of the extension.

A Technique for Magnetic Glass Particle-Mediated Nucleic Acid Extraction from Blood

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2025

This video demonstrates a technique for nucleic acid extraction from whole human blood using magnetic glass particles (MGPs) — small magnetic beads coated with silica. Upon lysing the blood cells using a lysis buffer, the released nucleic acids bind to the surface of silica-coated MGPs, extracting the molecules from the sample.

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

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Cited by 20 •

2015

Targeted cell delivery is useful in a variety of biomedical applications. The goal of this protocol is to use superparamagnetic iron oxide nanoparticles (SPION) to label cells and thereby enable magnetic cell targeting approaches for a high degree of control over cell delivery and localization.

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