Mini Slot Die Coater

Mini slot die coating is a laboratory-scale thin-film deposition technique that applies a controlled liquid layer to a moving substrate, enabling reproducible fabrication with minimal material use. In operation, a solution or suspension is pumped through a narrow slot onto the substrate, while flow rate, coating speed, die-to-substrate gap, and fluid properties determine film thickness and uniformity. In biology, the method can prepare functional coatings for cell culture surfaces, biosensors, biomaterial scaffolds, and drug-delivery studies when compatible formulations are used. Its precise, scalable control supports systematic testing of surface chemistry, topography, and biological responses in research and development.

Mini Slot Die Coater - Related Videos

Education

JoVE Core - Introduction to Psychology

Kubler Ross's Stages of Dying

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2025

Elisabeth Kübler-Ross significantly advanced psychology's understanding of the process of dying with her influential book, On Death and Dying (1969). She focused on studying terminally ill individuals and outlined five stages commonly experienced when coping with death: denial, anger, bargaining, depression, and acceptance. In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from emotional distress. Anger...

Research

JoVE Journal - Engineering

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies

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Cited by 5 •

2015

We demonstrate the use of the Laser-induced Forward Transfer (LIFT) technique for flip-chip assembly of optoelectronic components. This approach provides a simple, cost-effective, low-temperature, fast and flexible solution for fine-pitch bumping and bonding on chip-scale for achieving high-density circuits for optoelectronic applications.

Quantitative Analyses of all Influenza Type A Viral Hemagglutinins and Neuraminidases using Universal Antibodies in Simple Slot Blot Assays

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Cited by 19 •

2011

A simple slot blot method was developed for the quantification of influenza viral hemagglutinin and neuraminidase using universal antibodies targeting their most conserved sequences identified through bioinformatics analyses. This innovative approach may provide a useful alternative to quantitative determination of all viral hemagglutinin and neuraminidase.

Examination of Proteins Bound to Nascent DNA in Mammalian Cells Using BrdU-ChIP-Slot-Western Technique

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Cited by 4 •

2016

In this protocol, we describe a novel BrdU-ChIP-Slot-Western technique to examine proteins and histone modifications associated with newly synthesized or nascent DNA.

Research

JoVE Journal - Medicine
Free Sample

Novel Mini-open Transforaminal Lumbar Interbody Fusion

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2025

The protocol introduces a novel mini-open TLIF, which can significantly reduce intraoperative blood loss, achieving minimally invasive outcomes with enhanced recovery.

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