Neuron Device

A neuron device is an engineered tool that interfaces with nerve cells to monitor, stimulate, or manipulate their electrical activity, supporting research into how nervous systems function. These devices typically use electrodes or other biointerfaces to detect voltage changes generated by neuronal signaling or deliver controlled electrical pulses that alter membrane activity. In biology, neuron devices help researchers investigate synaptic communication, neural circuits, and responses to stimulation under controlled experimental conditions. They also support the development of brain-computer interfaces, neuroprosthetic systems, and therapeutic technologies for restoring or modulating neural function.

Neuron Device - Related Videos

Research

JoVE Journal - Biology
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Fabrication of a Microfluidic Device for the Compartmentalization of Neuron Soma and Axons

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Cited by 14 •

2007

In this video we demonstrate the technique of soft lithography with polydimethyl siloxane (PDMS) which we use to farbricate a microfluidic device for culturing neurons.

Research

JoVE Journal - Biology
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Preparing E18 Cortical Rat Neurons for Compartmentalization in a Microfluidic Device

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Cited by 26 •

2007

In this video we demonstrate the preparation of E18 Cortical Rat Neurons.

Research

JoVE EoE - Neuronal Culture Techniques

Differentiation of Neural Stem Cells to Neurons Using a Compartmentalized Microfluidic Device

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2025

The video demonstrates the differentiation of neural stem cells (NSCs) using a microfluidic device comprising a somatic and an axonal compartment separated by a microgroove barrier. NSCs are introduced into the somatic compartment and are allowed to adhere. The NSCs differentiate into neurons inside the somatic compartment and extend axons through the microgroove barrier to the axonal compartment.

Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection

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Cited by 8 •

2017

This procedure describes how to rapidly initiate, extend and connect neurites organized in microfluidic chambers using poly-D-lysine-coated beads fixed to micropipettes that guide neurite elongation.

Tracking Axonal Transport of Organelles in Motor Neurons Using a Microfluidic Device

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2025

This video demonstrates a method for tracking axonal transport in motor neurons using a microfluidic chamber system. It involves culturing mouse embryonic spinal cord tissues in polymer-coated wells with nutrient medium to induce axonal growth. The movement of fluorescent dye-stained organelles in live imaging, confirms the bidirectional axonal transport.

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