Neuro Precursor Cells

Neuro precursor cells are immature neural cells that can self-renew and generate specialized cell types of the nervous system, making them important for understanding brain development and repair. Their behavior is regulated by local cellular signals and growth factors that control proliferation, maintenance of precursor identity, and differentiation into neurons or glial cells. In biology research, these cells support studies of neurogenesis, neural development, and neurological disease, while cultured precursor populations provide models for investigating genetic and environmental effects on the nervous system. Their capacity for cell production also informs research on tissue regeneration and potential cell-based therapies.

Neuro Precursor Cells - Related Videos

Research

JoVE Journal - Biology

Culture of Mouse Neural Stem Cell Precursors

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Cited by 38 •

2007

This video describes the method used for isolation of neuroprecursors from the developing cortex of embryonic mice. The procedure for removing embryos from the uterus, dissecting the cortical tissue, and digesting the isolated cerebral cortex is shown.

Research

JoVE Journal - Biology
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Differentiation of Embryonic Stem Cells into Oligodendrocyte Precursors

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Cited by 28 •

2010

We describe a small molecule-based protocol for differentiation of mouse embryonic stem cells into oligodendrocyte precursor cells (OPCs). This protocol generates Olig2+NG2+ OPCs with high efficiency by 30 days of differentiation. We also describe a method to generate "spiking" OPCs that can fire action potentials.

Isolation and Expansion of Adult Canine Hippocampal Neural Precursors

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Cited by 3 •

2016

The canine brain is a valuable model in which to study adult neurogenesis. Presented here are protocols for isolating and expanding adult canine hippocampal neural precursor cells from primary brain tissue.

Transplantation of Interneuron Precursor Cells into the Brain of a Mouse Pup

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2025

Source: Quattrocolo, G., et al. Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains. J. Vis. Exp. (2018)This video demonstrates the transplantation of interneuron precursor cells into the neonatal mouse brain using either a homotopic or heterotopic approach. The procedure involves securing an anesthetized recipient pup, identifying the target brain region, and injecting a suspension of precursor cells derived from a donor pup at the same developmental stage.

Culture of myeloid dendritic cells from bone marrow precursors

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Cited by 22 •

2008

This video demonstrates the procedure for differentiating myeloid dendritic cells from mouse bone marrow. Isolation of mouse tibia and femur, and processing of bone marrow are demonstrated. Pictures demonstrating cell morphology before and after differentiation, and figures depicting cell phenotype and IL-12 production following maturation using CpG are shown.

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