Closed Chest Catheterization
Closed Chest Catheterization - Related Videos
08:21
Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
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Cited by 11 •
2020
Presented here is a protocol to assess biventricular heart function in mice by generating pressure-volume (PV) loops from the right and left ventricle in the same animal using closed chest catheterization. The focus is on the technical aspect of surgery and data acquisition.
13:42
A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion
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Cited by 19 •
2012
Surgical trauma induces an inflammatory response. Cytokines and endogenous ligands are known to modulate myocardial infarct size following ischemia and reperfusion. We present a modified closed-chest model of murine ischemia and reperfusion using hanging weights to minimize effects of thoracotomy.
09:47
A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
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Cited by 26 •
2015
This article describes a rat model of electrically-induced ventricular fibrillation and resuscitation by chest compression, ventilation, and delivery of electrical shocks that simulates an episode of sudden cardiac arrest and conventional cardiopulmonary resuscitation. The model enables gathering insights on the pathophysiology of cardiac arrest and exploration of new resuscitation strategies.
08:10
A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
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Cited by 20 •
2018
Here, we present a protocol of Transverse Aortic constriction (TAC) via a lateral thoracotomy. This technique is a minimally invasive, closed chest surgical procedure aiming to simulate pressure overload and heart failure in mice utilizing standard TAC laboratory settings.
13:26
Basic Surgical Techniques in the Göttingen Minipig: Intubation, Bladder Catheterization, Femoral Vessel Catheterization, and Transcardial Perfusion
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Cited by 46 •
2011
The use of domestic and miniature pigs in science has increased significantly in recent years. By demonstrating how to perform intubation, transurethral bladder catheterization, femoral artery and vein catheterization, as well as transcardial perfusion, we aim to further increase the value of Göttingen minipigs in biomedical research.
FAQs
An underwater seal permits material and air to move outward from the pleural space while limiting air entry in the opposite direction. Controlled suction provides an additional means of managing drainage conditions. Together, these drainage-system options support removal of unwanted pleural contents while helping preserve the pressure conditions needed for lung expansion.
Restoring negative intrapleural pressure is central because pressure within the pleural space affects whether the lung can expand normally. When air, blood, or fluid accumulates, drainage helps reestablish that pressure environment. The clinical goal is improved breathing through renewed lung expansion, rather than simply removing fluid or air alone.
Proper placement determines whether the catheter can effectively reach the pleural space and drain its contents. The procedure advances the catheter between the ribs, then connects it to a drainage system. Monitoring after placement is important because effective positioning and ongoing drainage are linked to restoring pressure and supporting lung expansion.
The same drainage approach can address different pleural-space problems, but the material being removed reflects the underlying disorder. Air is associated with pneumothorax, blood with hemothorax, and excess fluid with pleural effusion. Recognizing this relationship connects the catheter’s immediate function with diagnosis and treatment of the chest condition.
Preparation includes local anesthesia and sterile preparation of the chest. The catheter is then advanced between the ribs into the pleural space and attached to an underwater-seal or controlled-suction drainage system. This sequence allows removal of accumulated air, blood, or fluid while limiting air entry and supporting restoration of normal lung expansion.
Monitoring focuses on whether catheter placement and drainage are producing the intended physiological response. Successful management should help reestablish negative intrapleural pressure, improve breathing, and promote lung expansion. These outcomes also help clinicians assess whether the drainage setup is functioning as intended during treatment of a pleural-space disorder.
Clinicians may use this approach for pneumothorax, hemothorax, pleural effusion, and postoperative thoracic drainage. These indications cover accumulation of air, blood, or fluid as well as planned drainage after thoracic surgery. Its minimally invasive access through the chest wall makes it relevant across pleural-space problems and postoperative care.