Thoracolumbar Fractures

Thoracolumbar fractures are injuries affecting the transition between the thoracic and lumbar regions of the spine, where structural damage can compromise spinal stability and neural function. They commonly result from axial loading, flexion, rotation, or high-energy trauma that disrupts the vertebral body, posterior elements, or supporting ligaments; burst fractures may force bone fragments into the spinal canal. Clinical examination and imaging, particularly computed tomography and magnetic resonance imaging, help define fracture morphology, ligament injury, and neurological risk. Classification and stability assessment guide decisions about observation, bracing, or surgical fixation, improving treatment planning and reducing the risk of deformity or neurological deterioration.

Thoracolumbar Fractures - Related Videos

Research

JoVE Journal - Medicine

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

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2024

The sagittal adjusting screw (SAS) system has been widely used for thoracolumbar (TL) spinal trauma. Percutaneous options and specialized trauma reduction devices are also available for the SAS system. We describe a technique for reducing TL burst fractures using an SAS system and a newly introduced trauma reduction device.

Research

JoVE Journal - Biology

Development of a Novel Internal Fixation Model for Rat Radial Fractures: Fracture Healing Assessment and Dorsal Root Ganglion Isolation

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2026

The study innovatively combines sutures and titanium needles for stable internal fixation in a rat radial fracture model. Fracture healing was assessed via micro-computed tomography (micro-CT), and primary dorsal root ganglion (DRG) neurons were isolated and cultured for further investigation.

A Method for Studying the Temperature Dependence of Dynamic Fracture and Fragmentation

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Cited by 1 •

2015

Fracture and fragmentation are late stage phenomena in dynamic loading scenarios and are typically studied using explosives. We present a technique for driving expansion using a gas gun which uniquely enables control of both loading rate and sample temperature.

Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair

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Cited by 13 •

2014

Quantitative measurement of bone progenitor function in fracture healing requires high resolution serial imaging technology. Here, protocols are provided for using intravital microscopy and osteo-lineage tracking to sequentially image and quantify the migration, proliferation and differentiation of endogenous osteogenic stem/progenitor cells in the process of repairing bone fracture.

Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy

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Cited by 6 •

2014

Basic techniques and refinements of freeze-fracture processing of biological specimens and nanomaterials for examination by transmission electron microscopy are described. This technique is a preferred method for revealing ultrastructural features and specializations of biological membranes and for obtaining ultrastructural level dimensional and spatial data in materials sciences and nanotechnology products.

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