Cruciate Ligaments
Cruciate Ligaments - Related Videos
10:32
Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
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Cited by 11 •
2015
Animal models are important tools for the evaluation of tissue-engineered grafts. This paper presents the protocol for preparing an electrospun biodegradable polymer graft for use in anterior cruciate ligament tissue engineering, as well as a surgical protocol for implantation in a rat model.
06:28
Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
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2025
Herein, we describe a surgical method to transect the anterior cruciate ligament (ACL) as a reliable model to induce knee osteoarthritis in rodents and methodologies for harvesting knee synovial fluid, measuring knee edema, and assessing osteoarthritis severity.
08:30
Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
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Cited by 11 •
2014
For future applications as a patch to repair partial tears of the Anterior Cruciate Ligament (ACL), human ACL derived cells were isolated from tissue obtained during reconstructive procedures, expanded in vitro and grown on tissue engineered scaffolds. Cellular adhesion and morphology was then performed to confirm biocompatibility on scaffold surface.
05:44
Arthroscopic Excision of Posterior Cruciate Ligament Cysts Using a Double Posteromedial Approach
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2023
We present a surgical approach to treat posterior cruciate ligament cysts by an arthroscopic double posteromedial approach.
05:07
Early Weight-Bearing Rehabilitation Protocol After Anterior Cruciate Ligament Reconstruction
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Cited by 4 •
2024
Based on the safety and feasibility, this article presents an early weight-bearing rehabilitation protocol after anterior cruciate ligament reconstruction. The protocol is clear and easy to operate, which is helpful to promote its use in clinical practice and accelerate the functional recovery of patients.
FAQs
Their mechanical behavior depends on joint position. As the knee changes angle, different portions of the collagen fibers become taut, altering how the ligaments restrain movement. This position-dependent tension helps limit excessive forward and backward translation while also controlling rotation. Consequently, stability is not a single fixed property but a coordinated response across movement.
Anterior and posterior cruciate ligaments contribute to stability as a paired system rather than acting in isolation. Their crossing arrangement helps regulate the relationship between the femur and tibia, while changing fiber tension guides that relationship through motion. Studying both structures therefore helps explain how the knee combines controlled translation, rotation, and movement.
The crossing geometry gives the ligaments a way to influence motion in more than one direction. Their dense connective-tissue organization transmits tension as the joint moves, helping guide femur-tibia alignment while limiting unwanted translation and rotation. This makes the arrangement relevant to biological studies of joint stability and to biomechanical assessment of knee function.
Researchers approach them through complementary anatomical, biomechanical, and injury-model perspectives. Anatomy describes organization, biomechanics examines how tension relates to movement, and injury models help investigate what happens when that stabilizing system is damaged. Together, these approaches connect tissue structure with joint function and support evaluation of diagnostic and reconstructive strategies.
Injury models provide a framework for examining sprains and tears in relation to altered joint stability. By connecting damage with changes in movement control, investigators can study the biological and mechanical consequences of ligament failure. These models also help evaluate reconstruction strategies and contribute to research on recovery, rehabilitation, and long-term joint health.
Reconstruction strategies are evaluated against the ligaments’ normal biomechanical role: restoring a stable relationship between the femur and tibia while controlling excessive translation and rotation. Healing and rehabilitation research extends this question beyond the initial injury by considering connective-tissue recovery and subsequent joint health. The combined perspective links treatment evaluation with the broader biology of tissue repair.